TPC Working Groups are grass-roots sub-communities with shared interest and who are pursing collaboration in specific areas. The current working groups are listed below. New working groups are encouraged where there is critical mass of interest and at least two leaders (from different institutions, ideally in different geographical regions) interested in organizing.

• Data Preparation, Training, and Workflows
• Domain: Accelerators and Living Documents
• Domain: Biology, Biochemistry, and Bioinformatics
• Domain: Cancer
• Domain: Climate, Environment, and Ecology
• Domain: Engineering, Energy, and Mechanics
• Domain: Fundamental Physics and Cosmology
• Domain: Materials, Chemistry, and Nanoscience
• Ethics
• Large Language Models for Scientific Software
• Model Architecture and Compute Performance
• Model Skills, Safety and Trust Evaluation
• Outreach and Training